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人小细胞肺癌定量PCR芯片试剂盒

英文名:GeneQuery™ Human Small Cell Lung Cancer qPCR Array Kit
货号:GK032
价格:¥4320.00
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

人小细胞肺癌定量PCR芯片试剂盒描述:



       ScienCell's GeneQuery™ Human Small Cell Lung Cancer qPCR Array Kit (GQH-SLC) is designed to facilitate gene expression profiling of 88 key genes involved in small cell lung cancer (SCLC) carcinogenesis. SCLC accounts for approximately 10-20% of all lung cancers. Compared to non-small cell lung cancer (NSCLC), SCLC usually grows and metastasizes more rapidly. Brief examples of how included genes may be grouped according to their functions are shown below:


       Oncogenes and tumor suppressor genes: MYC, RARB, FHIT, TP53, PTEN

       Cell cycle regulation and apoptosis: CDK2, CDK4, CDK6, CCND1, CCNE2, E2F2, CASP9

       PI3K/AKT pathway: PI3Ks, AKT1, AKT2

       IKK/NFKB pathway: NFKB1, CHUK, IKBKB


       GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that can specifically recognize and efficiently amplify a target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg2+, and no DMSO); (ii) the primer set recognizes all known transcript variants of target gene, unless otherwise indicated; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis, and gel electrophoresis.


       GeneQuery™ Human Small Cell Lung Cancer qPCR Array Plate Layout*(8 controls in Bold and Italic)



 

1

2

3

4

5

6

7

8

9

10

11

12

A

ABCB1

CCND1

CHUK

CSF3

HTATIP2

KRT19

LAMB2

MYCL

PIK3CA

PTK2

SYP

β-actin

B

ABCC1

CCNE2

CKS1B

CXCR2

IKBKB

KRT20

LAMB3

NCAM1

PIK3CD

RARB

TOP1

GAPDH

C

AKT1

CDK2

CKS2

CYCS

ITGA2

KRT7

LAMB4

NFKB1

PIK3CG

RASSF1

TP53

LDHA

D

AKT2

CDK4

COL4A1

E2F2

ITGA2B

LAMA1

LAMC1

NKX2-1

PIK3R1

RCVRN

TRAF1

NONO

E

APAF1

CDK6

COL4A2

EGFR

ITGA3

LAMA2

LAMC2

NMB

PIK3R3

RXRA

TRAF4

PPIH

F

BIRC2

CDKN1B

COL4A4

ENO2

ITGAV

LAMA3

LAMC3

NMBR

PIK3R5

RXRG

TRAF5

GDC

G

BIRC7

CDKN2A

COL4A5

FHIT

ITGB1

LAMA5

MAX

NOS2

PTEN

SKP2

TRAF6

PPC

H

CASP9

CHGA

COL4A6

FN1

KIT

LAMB1

MYC

PIAS2

PTGS2

SST

XIAP

NTC

 

* gene selection may be updated based on new research and development


产品使用说明:仅供科研研究使用

货号

GK032

产地

美国

缩写

GQH-SLC

规格

One 96-well plate, one 20ul reaction per well

用途

科研

保存

4°C or -20°C

运输

常温

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