Ultrastructural features reported for HT-29 cells include microvilli, microfilaments, large vacuolated mitochondria with dark granules, smooth and rough endoplasmic reticulum with free ribosomes, lipid droplets, few primary and many secondary lysosomes. 

The cells express urokinase receptors, but do not have detectable plasminogen activator activity [PubMed ID: 8381394]. HT-29 cells are negative for CD4, but there is cell surface expression of galactose ceramide (a possible alternative receptor for HIV). 

The line is positive for expression of c-myc, K-ras, H-ras, N-ras, Myb, sis and fos oncogenes. The p53 antigen is overproduced, and there is a G -> A mutation in codon 273 of the p53 gene resulting in an Arg -> His substitution. N-myc oncogene expression was not detected.

There is a G -> A mutation in codon 273 of the p53 gene resulting in an Arg -> His substitution.

论文标题： MiR-21-5p Induces Pyroptosis in Colorectal Cancer via TGFBI
DOI： 10.3389/fonc.2020.610545
发表时间： 2021-02-05
期刊： Frontiers in Oncology
影响因子： 6.244
货号： ZQ0057
产品名称： HT-29 cells
原文链接： https://pubmed.ncbi.nlm.nih.gov/33614494/

论文标题： Knockdown of SFRS9 Inhibits Progression of Colorectal Cancer Through Triggering Ferroptosis Mediated by GPX4 Reduction
DOI： 10.3389/fonc.2021.683589
发表时间： 2021-07-16
期刊： Frontiers in Oncology
影响因子： 6.244
货号： ZQ0057
产品名称： HT29 cells
原文链接： https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8322952/

论文标题： Integrating network pharmacology deciphers the action mechanism of Zuojin capsule in suppressing colorectal cancer
DOI： 10.1016/j.phymed.2021.153881
发表时间： 2021-12-09
期刊： PHYTOMEDICINE
影响因子： 5.34
货号： ZQ0057
产品名称： HT29 cells

原文链接： https://www.sciencedirect.com/science/article/pii/S0944711321004219

论文标题： PRDX2 removal inhibits the cell cycle and autophagy in colorectal cancer cells
DOI： 10.18632/aging.103690
发表时间： 2020-07-20
期刊： Aging-US
影响因子： 4.831
货号： ZQ0057
产品名称： HT29 cells
原文链接： https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485722/

论文标题： Noninvasive Evaluation of EGFR Expression of Digestive Tumors Using 99mTc-MAG3-Cet-F(ab)2-Based SPECT/CT Imaging
DOI： 10.1155/2022/3748315
发表时间： 2022-06-24
期刊： Molecular Imaging
影响因子： 4.488
货号： ZQ0057
产品名称： HT29 cells
原文链接： https://www.hindawi.com/journals/moi/2022/3748315/