The Ultra-Low Binding Culture Plates prevent cell attachment by providing a neutrally charged, hydrophilic surface. Each plate is specially treated with a hydrogel that is animal-component free, inert and biocompatible. These plates are useful for the cultures of human mammary stem cells, progenitor cells, neural stem cells and neurospheres. Additionally, plates can be used in the in vitro differentiation of human and mouse pluripotent stem cells via embryoïd body formation.