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0.2%肝素
英文名:0.2% Heparin, 5 ml
货号:0863
价格:¥1460.00
浏览量:1649次
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  • 产品说明
  • 产品规格
  • 参考文献
  • 常见问题

0.2%肝素描述:


      Heparin is a 10-12 kDa polysaccharide produced in mast cells. Heparin inhibits blood coagulation through binding and activation of anti-thrombin [1] and acts as a cofactor to basic Fibroblast Growth Factor-2 (bFGF) [2, 3, 4].


        The effect of heparin on cell growth and morphology in vitro is cell-type dependent and may promote or inhibit cell proliferation. Culture media may be supplemented with heparin solution (HEP) at 1:1000-1:100 (0.4 – 4.0 U/mL). The optimal concentration should be determined for individual cell types and culture conditions.


Concentration

2 mg/mL heparin sodium salt (from porcine intestinal mucosa) in Dulbecco’s Phosphate-Buffered Saline, sterile-filtered. Potency: 200 Units per milligram*.

*Units are USP (United States Pharmacopeia units) and indicate heparin potency by weight. Units are not evaluated by ScienCell but are provided by supplier.


产品使用说明:仅供科研研究使用

货号

0863

产地

美国

缩写

HEP

规格

5 ml

用途

科研

包装

管装

保存

4

运输

胶冰

参考文献


[1] Bjork I and Lindahl U. (1982) "Mechanism of the anticoagulant action of heparin". Mol Cell Biochem, 48(3):161-82. 
[2] Rapraeger AC, Krufka A and Olwin BB. (1991) "Requirement of heparin sulfate for bFGF-mediated fibroflast growth and myoblast differentiation". Science. 252(5013):1705-8.
[3] Roghani M, Mansukhani A, et al. (1994) "Heparin increases the affinity of basic fibroblast growth factor for its receptor but is not required for binding". J Biol Chem. 269(6):3976-84.
[4] Sasisekharan R, Ernst S and Venkataraman G. (1997) "On the regulation of fibroblast growth factor activity by heparin-like glycosaminoglycans". Angiogenesis, 1(1):45-54.


[1] Bjork I and Lindahl U. (1982) "Mechanism of the anticoagulant action of heparin". Mol Cell Biochem, 48(3):161-82. 


[2] Rapraeger AC, Krufka A and Olwin BB. (1991) "Requirement of heparin sulfate for bFGF-mediated fibroflast growth and myoblast differentiation". Science. 252(5013):1705-8.


[3] Roghani M, Mansukhani A, et al. (1994) "Heparin increases the affinity of basic fibroblast growth factor for its receptor but is not required for binding". J Biol Chem. 269(6):3976-84.


[4] Sasisekharan R, Ernst S and Venkataraman G. (1997) "On the regulation of fibroblast growth factor activity by heparin-like glycosaminoglycans". Angiogenesis, 1(1):45-54.

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